![Cancers | Free Full-Text | Ibrutinib Resistance Mechanisms and Treatment Strategies for B-Cell Lymphomas Cancers | Free Full-Text | Ibrutinib Resistance Mechanisms and Treatment Strategies for B-Cell Lymphomas](https://www.mdpi.com/cancers/cancers-12-01328/article_deploy/html/images/cancers-12-01328-g001.png)
Cancers | Free Full-Text | Ibrutinib Resistance Mechanisms and Treatment Strategies for B-Cell Lymphomas
![Resistance to BTK inhibition by ibrutinib can be overcome by preventing FOXO3a nuclear export and PI3K/AKT activation in B-cell lymphoid malignancies | Cell Death & Disease Resistance to BTK inhibition by ibrutinib can be overcome by preventing FOXO3a nuclear export and PI3K/AKT activation in B-cell lymphoid malignancies | Cell Death & Disease](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41419-019-2158-0/MediaObjects/41419_2019_2158_Fig1_HTML.png)
Resistance to BTK inhibition by ibrutinib can be overcome by preventing FOXO3a nuclear export and PI3K/AKT activation in B-cell lymphoid malignancies | Cell Death & Disease
![Randomized Phase III Trial of Ibrutinib and Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Non–Germinal Center B-Cell Diffuse Large B-Cell Lymphoma | Journal of Clinical Oncology Randomized Phase III Trial of Ibrutinib and Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Non–Germinal Center B-Cell Diffuse Large B-Cell Lymphoma | Journal of Clinical Oncology](https://ascopubs.org/cms/10.1200/JCO.18.02403/asset/images/large/jco.18.02403f2.jpeg)
Randomized Phase III Trial of Ibrutinib and Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Non–Germinal Center B-Cell Diffuse Large B-Cell Lymphoma | Journal of Clinical Oncology
![Cancers | Free Full-Text | Regulation of B-Cell Receptor Signaling and Its Therapeutic Relevance in Aggressive B-Cell Lymphomas Cancers | Free Full-Text | Regulation of B-Cell Receptor Signaling and Its Therapeutic Relevance in Aggressive B-Cell Lymphomas](https://pub.mdpi-res.com/cancers/cancers-14-00860/article_deploy/html/images/cancers-14-00860-g001.png?1644404399)
Cancers | Free Full-Text | Regulation of B-Cell Receptor Signaling and Its Therapeutic Relevance in Aggressive B-Cell Lymphomas
![Ibrutinib in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Retrospective Study | Indian Journal of Hematology and Blood Transfusion Ibrutinib in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Retrospective Study | Indian Journal of Hematology and Blood Transfusion](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs12288-021-01433-w/MediaObjects/12288_2021_1433_Fig3_HTML.png)
Ibrutinib in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Retrospective Study | Indian Journal of Hematology and Blood Transfusion
![Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma | Nature Medicine Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma | Nature Medicine](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fnm.3884/MediaObjects/41591_2015_Article_BFnm3884_Fig1_HTML.jpg)
Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma | Nature Medicine
![miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication | Cell Death & Disease miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication | Cell Death & Disease](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41419-023-06178-0/MediaObjects/41419_2023_6178_Figa_HTML.png)
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication | Cell Death & Disease
![JCI Insight - Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutations JCI Insight - Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutations](https://df6sxcketz7bb.cloudfront.net/manuscripts/90000/90196/medium/jci.insight.90196.f6.jpg)
JCI Insight - Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutations
![Overall survival following Richter transformation on ibrutinib by line... | Download Scientific Diagram Overall survival following Richter transformation on ibrutinib by line... | Download Scientific Diagram](https://www.researchgate.net/publication/363193523/figure/fig3/AS:11431281082645657@1662086926602/Overall-survival-following-Richter-transformation-on-ibrutinib-by-line-of-therapy-A-It.png)
Overall survival following Richter transformation on ibrutinib by line... | Download Scientific Diagram
![Combination of Enzastaurin and Ibrutinib synergistically induces anti-tumor effects in diffuse large B cell lymphoma | Journal of Experimental & Clinical Cancer Research | Full Text Combination of Enzastaurin and Ibrutinib synergistically induces anti-tumor effects in diffuse large B cell lymphoma | Journal of Experimental & Clinical Cancer Research | Full Text](https://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13046-019-1076-4/MediaObjects/13046_2019_1076_Fig2_HTML.png)
Combination of Enzastaurin and Ibrutinib synergistically induces anti-tumor effects in diffuse large B cell lymphoma | Journal of Experimental & Clinical Cancer Research | Full Text
![Combination of Enzastaurin and Ibrutinib synergistically induces anti-tumor effects in diffuse large B cell lymphoma | Journal of Experimental & Clinical Cancer Research | Full Text Combination of Enzastaurin and Ibrutinib synergistically induces anti-tumor effects in diffuse large B cell lymphoma | Journal of Experimental & Clinical Cancer Research | Full Text](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs13046-019-1076-4/MediaObjects/13046_2019_1076_Fig1_HTML.png)
Combination of Enzastaurin and Ibrutinib synergistically induces anti-tumor effects in diffuse large B cell lymphoma | Journal of Experimental & Clinical Cancer Research | Full Text
![Trial results show that younger lymphoma patients respond well to ibrutinib | Center for Cancer Research Trial results show that younger lymphoma patients respond well to ibrutinib | Center for Cancer Research](https://ccr.cancer.gov/sites/default/files/styles/quarter_1_1/public/staudt_467x267.jpg?h=0d20fbd6&itok=lED1dW4T)
Trial results show that younger lymphoma patients respond well to ibrutinib | Center for Cancer Research
![Ibrutinib in B-cell lymphoma: single fighter might be enough? | Cancer Cell International | Full Text Ibrutinib in B-cell lymphoma: single fighter might be enough? | Cancer Cell International | Full Text](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs12935-020-01518-y/MediaObjects/12935_2020_1518_Fig1_HTML.png)
Ibrutinib in B-cell lymphoma: single fighter might be enough? | Cancer Cell International | Full Text
![NIH study revises molecular classification for most common type of lymphoma | National Institutes of Health (NIH) NIH study revises molecular classification for most common type of lymphoma | National Institutes of Health (NIH)](https://www.nih.gov/sites/default/files/styles/featured_media_breakpoint-medium/public/news-events/news-releases/2018/20180411-molecular-diagnosis.jpg?itok=a5yjbV5z×tamp=1523465378)
NIH study revises molecular classification for most common type of lymphoma | National Institutes of Health (NIH)
![JPM | Free Full-Text | Relapsed/Refractory Diffuse Large B-Cell Lymphoma: A Look at the Approved and Emerging Therapies JPM | Free Full-Text | Relapsed/Refractory Diffuse Large B-Cell Lymphoma: A Look at the Approved and Emerging Therapies](https://www.mdpi.com/jpm/jpm-11-01345/article_deploy/html/images/jpm-11-01345-g001.png)
JPM | Free Full-Text | Relapsed/Refractory Diffuse Large B-Cell Lymphoma: A Look at the Approved and Emerging Therapies
![Ibrutinib in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Retrospective Study | Indian Journal of Hematology and Blood Transfusion Ibrutinib in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Retrospective Study | Indian Journal of Hematology and Blood Transfusion](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs12288-021-01433-w/MediaObjects/12288_2021_1433_Fig1_HTML.png)
Ibrutinib in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Retrospective Study | Indian Journal of Hematology and Blood Transfusion
![Ibrutinib combined with venetoclax for the treatment of relapsed/refractory diffuse large B cell lymphoma | Annals of Hematology Ibrutinib combined with venetoclax for the treatment of relapsed/refractory diffuse large B cell lymphoma | Annals of Hematology](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs00277-021-04535-7/MediaObjects/277_2021_4535_Fig1_HTML.png)